Interstellar Probe science objectives are shown at various distances along the trajectory. The yellow-orange color bar indicates the radial region where measurements are possible; the deepest orange is the prime region of interest. Among the objectives that are also possible are measurement of the cosmic infrared radiation background free from the zodiacal light, a survey >1 km size Kuiper Belt objects, a survey of organic matter in the outer solar system and the interstellar medium, and the identification of interstellar antiprotons arising from dark matter or primordial black holes.

In view of the fundamental contributions that Interstellar Probe would make to studies that include space plasma physics, planetary science, astrophysics, stellar and galactic evolution, and cosmology, it is important that NASA begin developing the technology required to carry out this truly exploratory mission.